Mifepristone: What It Is and How It Works

Mifepristone is a medicine that blocks progesterone, a hormone a pregnancy needs to keep going. In practical terms, it’s used mainly with misoprostol to end an early pregnancy and sometimes to treat Cushing’s syndrome. If you’re reading this because you or someone you care about needs reliable info, here’s a clear, no-nonsense summary of what to expect and what matters most.

How it’s used and what to expect

For medical abortion, mifepristone is usually taken first, followed 24–48 hours later by misoprostol. That second drug triggers uterine contractions to expel pregnancy tissue. Most people have cramping and bleeding similar to a heavy period or miscarriage; this is expected. The standard window for this combination is up to about 10 weeks of pregnancy in many places, but local rules and doctor advice vary, so check with a clinician before you act.

Safety, side effects, and when to call for help

Common side effects include bleeding, cramps, nausea, and tiredness. Heavy bleeding (soaking through two pads per hour for more than two hours), severe pain that doesn’t ease with pain relievers, or fever over 38°C (100.4°F) for more than 24 hours are signs to seek medical attention. Serious complications are rare but can happen. If you have an IUD, an ectopic pregnancy, an allergy to the medicine, or certain chronic conditions, mifepristone may not be safe for you—talk to a clinician first.

Drug interactions matter. Some medications and herbal products can reduce how well mifepristone works or change side effects. Tell your provider about all medicines and supplements you take, including stronger antibiotics, seizure meds, and St. John’s wort.

Follow-up is often recommended. You might need a visit or a pregnancy test after a couple of weeks to confirm the procedure worked. If bleeding continues and pregnancy symptoms persist, contact your healthcare provider for imaging or blood tests.

Want to get mifepristone? It should be prescribed and provided by a licensed clinician. Avoid buying pills from unknown online sellers without a prescription. Counterfeit or incorrect medicines increase risk. If access is limited where you live, look for trusted telemedicine services or clinics that follow local law and medical standards.

Practical tips: confirm how far along the pregnancy is before taking anything; arrange someone to stay with you if you expect heavy bleeding; stock pads, pain relievers (as advised), and a prearranged contact number for your clinic. Keep records of any prescriptions and instructions you receive.

If you have questions about dosing, legality where you live, or side effects, a healthcare provider, clinic nurse, or reputable telehealth service can give tailored advice. Mifepristone is safe and effective when used under proper medical guidance—but like any medical treatment, it works best with clear information and support.