Tag: antihistamines and alcohol

Antihistamines and Alcohol: Why Mixing Them Increases Drowsiness Dangerously

Antihistamines and Alcohol: Why Mixing Them Increases Drowsiness Dangerously

Feb 25 2026 / Medications

Mixing antihistamines with alcohol can dangerously increase drowsiness, impairing reaction time and increasing accident risk. First-generation drugs like Benadryl are especially risky, but even 'non-drowsy' options like Claritin and Zyrtec aren't safe with alcohol.

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